abstract：OBJECTIVE:To characterize the temporal course of transcranial magnetic stimulation-induced phosphene thresholds in subjects with migraine and in controls. METHODS:Eleven subjects with migraine with aura, 10 subjects with migraine without aura, 9 subjects with menstrual migraine, and 15 controls (no history of migraine...

journal_title：Headache

authors： Young WB,Oshinsky ML,Shechter AL,Gebeline-Myers C,Bradley KC,Wassermann EM

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a sympathetic block at C7 on cluster headache. BACKGROUND:Eleven patients presenting to a pain control unit with cluster headache were included in the study after giving informed consent. METHODS:In all patients, a mixture of 5 mL of 0.5% bupivacaine hydrochloride and 1 cc of meth...

journal_title：Headache

authors： Albertyn J,Barry R,Odendaal CL

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Migraine has been reported as a possible risk factor for ischemic stroke. The mechanisms underlying this association are unknown. OBJECTIVES:To evaluate cerebrovascular reactivity to hypercapnia in the anterior and posterior circulation of patients with migraine, as reduced cerebrovascular reactivity is ass...

journal_title：Headache

authors： Silvestrini M,Baruffaldi R,Bartolini M,Vernieri F,Lanciotti C,Matteis M,Troisi E,Provinciali L

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To assess the degree of debilitation and the treatment views of individuals with headache presenting to a community pharmacy. BACKGROUND:Migraine and chronic daily headache are common poorly managed illnesses. Pharmacists recommend an over-the-counter "headache product" to customers more than 53 000 times da...

journal_title：Headache

authors： Wenzel RG,Schommer JC,Marks TG

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Migraine can be disabling, but it varies greatly in frequency and intensity between individuals. It is not clear which clinical features have the greatest impact on a migraineur's quality of life. OBJECTIVE:To determine the influence of headache intensity and frequency on headache-related disability. METHO...

journal_title：Headache

authors： Magnusson JE,Becker WJ

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:To investigate the prevalence, clinical correlates, and treatment of migraine in bipolar disorder. BACKGROUND:The relationship between migraine and mood disorders has been of long-standing interest to researchers and clinicians. Although a strong association has been demonstrated consistently for migraine an...

journal_title：Headache

authors： Low NC,Du Fort GG,Cervantes P

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:This study examined somatic, psychological, and cognitive functioning of subjects with posttraumatic headache in comparison with multiple control groups. BACKGROUND:Posttraumatic headache is not as widely studied as other forms of headache (eg, tension-type, migraine). Previous research has suggested poor ps...

journal_title：Headache

authors： Tatrow K,Blanchard EB,Hickling EJ,Silverman DJ

更新日期：2003-07-01 00:00:00

abstract：:Botulinum toxin type A, a protein long used in the successful treatment of various dystonias, has a complex mechanism of action that results in muscle relaxation. At the neuromuscular junction, the presynaptic nerve ending is packed with synaptic vesicles filled with acetylcholine, and clustered at the tip of the fold...

journal_title：Headache

authors： Dolly O

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:To identify and investigate any dysfunction of neuromuscular transmission in episodic cluster headache. BACKGROUND:Abnormal neuromuscular transmission has been shown in migraine with aura and in migraine without aura by using single fiber electromyography. Especially for migraine with aura, a genetic cause h...

journal_title：Headache

authors： Ertas M,Baslo MB

更新日期：2003-06-01 00:00:00

abstract：:A 33-year-old woman developed persistent postural headache following epidural anesthesia (L2-L3 level). Iohexol myelography (L5-S1 puncture) demonstrated no epidural extravasation of contrast material (Figure A), but subsequent computed tomography (CT) axial images (B, C) revealed leakage of dye through the needle tra...

journal_title：Headache

authors： Goadsby P,Jager HR

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Migraine is a common cause of headache in adolescents. Assuming that the cerebral vasculature is involved in the pathophysiology of migraine, we compared cerebral vasoreactivity in adolescents both during a migraine attack and a headache-free interval. METHODS:A functional transcranial Doppler test utilizin...

journal_title：Headache

authors： Rosengarten B,Sperner J,Görgen-Pauly U,Kaps M

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:To study the therapeutic potential of the subcutaneous administration of Nalpha-methylhistamine in migraine prophylaxis. BACKGROUND:The histamine catabolite, Nalpha-methylhistamine, possesses a selective affinity for H3 receptors. We consequently considered it viable to conduct a clinical pharmacological stu...

journal_title：Headache

authors： Millán-Guerrero RO,Pineda-Lucatero AG,Hernández-Benjamín T,Tene CE,Pacheco MF

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of rizatriptan for acute migraine treatment and patient satisfaction with the drug in usual clinical practice settings. BACKGROUND:Although rizatriptan has been shown to effectively relieve migraine symptoms in clinical trials, we wished to assess its utility in typical patient ...

journal_title：Headache

authors： Jamieson D,Cutrer FM,Goldstein J,Dayno J,Hu XH,USMAP Investigators.

更新日期：2003-03-01 00:00:00

abstract：:The intimate relationship between sleep and headache has been recognized for centuries, yet the relationship remains clinically and nosologically complex. Headaches associated with nocturnal sleep have often been perceived as either the cause or result of disrupted sleep. An understanding of the anatomy and physiology...

journal_title：Headache

authors： Dodick DW,Eross EJ,Parish JM,Silber M

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Several studies suggest an association between migraine and juvenile stroke. Because of some shortcomings, we designed another case-control study of a homogenous group of patients with juvenile cerebral ischemia. This study is part of a larger German epidemiological research project on the association of mig...

journal_title：Headache

authors： Schwaag S,Nabavi DG,Frese A,Husstedt IW,Evers S

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:To test whether chronic headache (>3 days/week) is more prevalent than episodic headache (<3 days/week) in patients with a previous history of significant head trauma. METHOD:We included 903 consecutive patients referred to a specialist center for headache during a period of 2 years. As the main parameter, w...

journal_title：Headache

authors： Bekkelund SI,Salvesen R

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact on costs and outcomes of early migraine treatment with sumatriptan while pain is mild versus sumatriptan treatment of moderate to severe pain. BACKGROUND:Migraines result in substantial pain, impairment, and costs. Recent clinical studies have shown that early treatment with sumatripta...

journal_title：Headache

authors： Halpern MT,Lipton RB,Cady RK,Kwong WJ,Marlo KO,Batenhorst AS

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVES:In a randomized controlled trial extending over 6 months, we evaluated the effectiveness of acupuncture versus flunarizine in the prophylactic treatment of migraine without aura. METHODS:One hundred sixty women with migraines were randomly assigned to acupuncture treatment (group A, n = 80) or to an oral th...

journal_title：Headache

authors： Allais G,De Lorenzo C,Quirico PE,Airola G,Tolardo G,Mana O,Benedetto C

更新日期：2002-10-01 00:00:00

abstract：:The Kimmerle anomaly may be associated with a variety of neurological symptoms. We sought to determine the prevalence and character of these symptoms in a large cohort of afflicted patients. ...

journal_title：Headache

authors： Split W,Sawrasewicz-Rybak M

更新日期：2002-10-01 00:00:00

abstract：:The discussion about neuropsychological sequalae from migraine occurring in adults is controversial. The purpose of our study was to examine whether children with migraine may be at risk for impaired intellectual development compared with their siblings free of migraine. ...

journal_title：Headache

authors： Haverkamp F,Hönscheid A,Müller-Sinik K

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE AND BACKGROUND:Serotonergic mechanisms play an important role in the pathogenesis of headache. To search for potential indicators of altered serotonin homeostasis in migraine, we have investigated three parameters of the platelet serotonin (5HT) system, platelet serotonin level (PSL), platelet serotonin uptak...

journal_title：Headache

authors： Jernej B,Vladić A,Cicin-Sain L,Hranilović D,Banović M,Balija M,Bilić E,Sucić Z,Vukadin S,Grgicević D

更新日期：2002-07-01 00:00:00

abstract：:A person's response to pain treatment may be due to factors other than the direct effect of analgesics. Amelioration of pain is often associated with modalities that appear to make no scientific sense. This review outlines the mechanisms of pain amelioration other than that by medication. These mechanisms help to expl...

journal_title：Headache

authors： Solomon S

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Olanzapine, a thienobenzodiazepine, is a new "atypical" antipsychotic drug. Olanzapine's pharmacologic properties suggest it would be effective for headaches, and its propensity for inducing acute extrapyramidal reactions or tardive dyskinesia is relatively low. We thus decided to assess the value of olanzap...

journal_title：Headache

authors： Silberstein SD,Peres MF,Hopkins MM,Shechter AL,Young WB,Rozen TD

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:To determine the pharmacological profile of frovatriptan. BACKGROUND:Frovatriptan is a new 5-HT(1B/1D) agonist developed for the treatment of migraine. METHODS:Pharmacological studies were performed using in vitro and in vivo techniques. RESULTS:Radioligand-binding studies showed that frovatriptan has a hi...

journal_title：Headache

authors： Comer MB

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of mouth-dispersible aspirin 900 mg and placebo in the treatment of migraine. BACKGROUND:Aspirin is widely accepted as an effective therapy for migraine. Previous studies have indicated that gastric stasis and delayed gastric emptying, which occur during migraine attacks, delay aspiri...

journal_title：Headache

authors： MacGregor EA,Dowson A,Davies PT

更新日期：2002-04-01 00:00:00

abstract：:We report the case of a man who suffered from Valsalva-induced cluster headaches. The headaches deviated from classic cluster in that they were solely induced by activity involving the Valsalva maneuver, such as coughing and sneezing, and never occurred spontaneously. The attacks were prevented by treatment with indom...

journal_title：Headache

authors： Ko J,Rozen TD

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To investigate similarities and differences between patients with cluster headache and patients with migraine. BACKGROUND:Patients with migraine and patients with cluster headache are considered, by many clinical neurologists, to be different psychologically and socially. METHODS:Twenty-five age-matched pai...

journal_title：Headache

authors： Blomkvist V,Hannerz J,Katz L,Theorell T

更新日期：2002-03-01 00:00:00

abstract：:We describe a patient with ophthalmoplegic migraine and right abducens nerve palsy, in whom serial magnetic resonance imaging showed a transient, gadolinium-enhancing lesion in the right lower pons, during both headache and the headache-free period. The enhancing linear lesion was felt to represent intraparenchymal fi...

journal_title：Headache

authors： Lee TG,Choi WS,Chung KC

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:To assess, in the setting of routine clinical practice, rizatriptan's effectiveness in treating acute migraine at its onset versus in a later phase of the attack. BACKGROUND:Although the efficacy and tolerability of rizatriptan have been well documented in clinical trials, no information is available about t...

journal_title：Headache

authors： Hu XH,Raskin NH,Cowan R,Markson LE,Berger ML,United States Migraine Study Protocol (USMAP) Group.

更新日期：2002-01-01 00:00:00

abstract：:Several second-generation triptans have been introduced that differ in their pharmacologic profiles relative to each other and to sumatriptan. As therapeutic options multiply, clinicians must be able to distinguish among these compounds. Recently, a meta-analysis was conducted on data from 53 double-blind, randomized,...

journal_title：Headache

authors： Ferrari MD

更新日期：2002-01-01 00:00:00

abstract：:Many patients with migraine believe weather is a trigger for their headaches. The objective of this study was to determine if very low frequency sferics, pulse-shaped electromagnetic fields originating from atmospheric discharges (lightning), are precipitating factors. The occurrence of sferics impulses is characteriz...

journal_title：Headache

authors： Vaitl D,Propson N,Stark R,Walter B,Schienle A

更新日期：2001-10-01 00:00:00

abstract：:A patient with chronic daily headaches developed overt signs of Cushing syndrome during treatment with serial occipital nerve block injections. Investigation demonstrated an exogenous source of corticosteroids as the cause of the Cushing syndrome in this patient, thus, implicating the corticosteroid component of the o...

journal_title：Headache

authors： Lavin PJ,Workman R

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:To investigate the impact of coumarin therapy on migraine attack frequency. BACKGROUND:Sporadic case reports and clinical studies have described beneficial effects of coumarin therapy on migraine severity. DESIGN AND METHODS:A retrospective follow-up study based on a prescription database covering a populat...

journal_title：Headache

authors： Rahimtoola H,Egberts AC,Buurma H,Tijssen CC,Leufkens HG

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:To describe the statuslike pattern of SUNCT (short-lasting unilateral neuralgiform pain with conjunctival injection and tearing) in two young women. BACKGROUND:SUNCT syndrome is a rare condition characterized by a short-lasting periocular pain associated with marked autonomic symptoms. Twenty-five cases have...

journal_title：Headache

authors： Montes E,Alberca R,Lozano P,Franco E,Martínez-Fernández E,Mir P

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:The periaqueductal gray matter (PAG) is at the center of a powerful descending antinociceptive neuronal network. We studied iron homeostasis in the PAG as an indicator of function in patients with episodic migraine (EM) between attacks and patients with chronic daily headache (CDH) during headache. High-resol...

journal_title：Headache

authors： Welch KM,Nagesh V,Aurora SK,Gelman N

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of migraine and episodic tension-type headache (ETTH) among university students as well as its impact on academic performance and quality of life. BACKGROUND:Headache is a very common symptom in clinical practice. The reduced capacities due to migraine can be profound, and more st...

journal_title：Headache

authors： Bigal ME,Bigal JM,Betti M,Bordini CA,Speciali JG

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:We conducted the present study to determine whether there are headache precipitating and aggravating factors that differentiate migraine from tension-type headache and headache precipitating and aggravating factors that differentiate tension-type headache from migraine. METHODS:We interviewed 38 patients wit...

journal_title：Headache

authors： Spierings EL,Ranke AH,Honkoop PC

更新日期：2001-06-01 00:00:00

abstract：:We describe a patient with atypical headache as the only presenting symptom of spontaneous triple cervical artery dissection. As the patient suffered from arterial hypertension, a causative relation between headache and arterial hypertension was initially taken into consideration. However, four-vessel arteriography di...

journal_title：Headache

authors： Buyle M,Engelborghs S,Kunnen J,De Deyn PP

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:To assess physician-patient communication about headache-related disability and to evaluate the influence of information about disability on physicians' perceptions of illness severity and the treatment needs of migraineurs. BACKGROUND:Evidence suggests that migraine is suboptimally treated in clinical pract...

journal_title：Headache

authors： Holmes WF,MacGregor EA,Sawyer JP,Lipton RB

更新日期：2001-04-01 00:00:00

abstract：:The present study evaluated the effects of relaxation treatment in 36 adolescents aged 13 to 18 years (mean +/- SD, 15.4 +/- 1.55 years) suffering from migraine or migraine and tension-type headache as compared with a waiting-list condition group. The subjects rated various characteristics of migraine and tension-type...

journal_title：Headache

authors： Fichtel A,Larsson B

更新日期：2001-03-01 00:00:00